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Next-Generation Chromatography
Category: Analytical Instruments
BIKAI UHPLC System | Ultra High Performance Liquid Chromatography (16,000 PSI)
4.8 out of 5 from 76 reviews
The BIKAI UHPLC system is an ultra high performance liquid chromatograph that withstands up to 16,000 PSI (1,100 bar), runs sub-2-micron columns, and comes in 1521 UHPLC and 1511 2D UHPLC configurations with diode array detectors, a 216-vial autosampler and FDA 21 CFR Part 11 compliant software.
For high-speed, high-resolution separations, the BIKAI UHPLC machine delivers stable performance at 16,000 PSI. Ultra-low dispersion flow cells and sub-2-micron columns cut run times and solvent use compared with conventional liquid chromatography.
Backed by EyouLab Enterprise software, it is built for pharmaceutical analysis, food safety testing, chemical analysis and advanced research labs. Global Bioscience Solutions supplies, installs and services the system across India.
- 16,000 PSI Pressure Tolerance
- FDA 21 CFR Part 11 Software
- 2D UHPLC Configurations
16,000 PSI
(1,100 Bar) Limit
(1,100 Bar) Limit
FDA 21 CFR
Part 11 Compliant
Part 11 Compliant
Ultra-Low
Dispersion Flow Cell
Dispersion Flow Cell
Dual-Dimensional
2D UHPLC
2D UHPLC
High-Throughput
Autosampler
Autosampler
Technical Specifications of the BIKAI UHPLC System
The BIKAI 1521 UHPLC and 1511 2D systems share one high-pressure platform. These are the core specifications.
| System Capabilities and Performance Data | |
|---|---|
| System Type | Ultra High Performance Liquid Chromatography (UHPLC) and 2D UHPLC |
| Max. Operating Pressure | 16,000 PSI (110 MPa, 1,100 bar) at 0 to 2 mL/min |
| Pump (Binary) | UP25 ultra high pressure binary gradient pump |
| Autosampler | A65 ultra high pressure (max 18,000 PSI), 100 µL loop |
| Autosampler Capacity | High throughput: up to 216 positions of 1.5 mL vials, or 4 x 96-well plates |
| Detector Options | D25 and D26 diode array detectors (DAD/PDA) |
| Wavelength Range | 190 nm to 640 nm (D25) | 190 nm to 800 nm (D26) |
| Flow Rate Range | 0.001 mL/min to 10.000 mL/min |
| Software Platform | EyouLab Enterprise, fully networkable, FDA 21 CFR Part 11 compliant |
UHPLC vs HPLC: Key Benefits and Differences
The main differences between UHPLC and HPLC are pressure limit, speed and resolving power.
| Factor | BIKAI UHPLC (1521) | BIKAI HPLC (1511) |
|---|---|---|
| Max. pressure | 16,000 PSI (1,100 bar) | 10,500 PSI |
| Column particles | Sub-2-micron | Conventional |
| Speed and resolution | Faster runs, higher resolution | Suited to conventional analysis |
| Best for | High throughput, complex separations | Routine QC and general analysis |
Compare configurations on the BIKAI HPLC system page.
- Pressure Tolerance for Finer ParticlesWithstand 16,000 PSI (1,100 bar) and use sub-2-micron particle columns to improve peak resolution beyond what standard HPLC allows.
- High Speed, Shorter Run TimesHigher pressure allows a higher mobile phase linear velocity without losing efficiency, so the UHPLC processes more samples per hour and uses less solvent.
- Ultra-Low Dispersion DetectorsThe D25 and D26 diode array detectors use optimized total reflection flow cells that reduce extra-column volume for sensitive trace compound detection.
- 2D UHPLC CapabilityThe 1511 2D UHPLC integrates dual-dimensional separation for complex matrices, improving productivity and reducing extensive sample pre-treatment.
- 21 CFR Part 11 Compliant SoftwareEyouLab Enterprise supports audit trails, system suitability tests (SST) and tiered user access for GMP and GLP labs.
UHPLC Applications: What Is a UHPLC System Used For?
- Pharmaceutical AnalysisStability-indicating API assays, rapid impurity profiling, and high-throughput drug testing and validation in FDA and GMP environments.
- Food Testing and Chemical AnalysisIdentify trace-level pesticides, mycotoxins and complex additives in food matrices where peak overlap is a problem.
- Research and BiotechnologySupport proteomics and metabolomics work, and biological compound isolation with 2D UHPLC methods.
How UHPLC Works
- Load samples into the A65 autosampler (up to 216 vials or 4 x 96-well plates).
- Pump the mobile phase with the UP25 binary gradient pump at pressures up to 16,000 PSI.
- Separate on a sub-2-micron column for high resolution in short run times.
- Detect compounds with the D25 or D26 diode array detector.
- Process and report in EyouLab Enterprise with a full audit trail.
Explore Related Laboratory Instruments
UHPLC System FAQs
What is the UHPLC system price in India?
The UHPLC machine price depends on the modules selected, such as the 1521 UHPLC or 1511 2D UHPLC, the D25 or D26 diode array detector and autosampler cooling options. Use the quote form or WhatsApp for a customized GST quotation.
What is the difference between UHPLC and HPLC?
UHPLC works at much higher pressure. The BIKAI UHPLC withstands up to 16,000 PSI (1,100 bar), which allows sub-2-micron columns that improve resolution, shorten run times and reduce solvent use. A conventional HPLC works at lower pressure, such as the BIKAI 1511 HPLC at 10,500 PSI.
What is a UHPLC system used for?
UHPLC is used for drug testing and validation, impurity profiling, food safety testing for pesticides and mycotoxins, chemical analysis, and research in proteomics, metabolomics and biotechnology where speed and resolution matter.
Is the UHPLC software suitable for a regulated pharmaceutical lab?
Yes. EyouLab Enterprise is FDA 21 CFR Part 11, GLP and GMP compliant, with audit trails, system suitability tests and tiered user access rights.
What is 2D UHPLC?
2D UHPLC integrates two-dimensional separation in one system. The BIKAI 1511 2D UHPLC improves productivity on complex matrices and reduces the need for extensive sample pre-treatment.
Are you UHPLC suppliers in Bangalore with installation and AMC support?
Yes. Global Bioscience Solutions in Bangalore supplies and installs the BIKAI UHPLC system across India, with validation support and AMC and calibration service.