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AutoGrid Rings & C-Clips – Essential Components for Cryo-EM Grid Preparation

AutoGrid Rings & C-Clips

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AutoGrid Rings & C-Clips are crucial components in Cryo-Electron Microscopy (Cryo-EM), enabling secure and stable grid mounting for high-resolution imaging. Designed specifically for Thermo Fisher Scientific Autogrids and Cryo-EM autoloader systems, these precision-engineered components ensure optimal grid handling, reduced mechanical stress, and enhanced sample integrity.

 

The C-clip rings securely lock the Cryo-EM grid into the AutoGrid ring, ensuring proper positioning for high-throughput Cryo-EM workflows and automated data collection. These components are manufactured with high-quality materials to withstand cryogenic conditions, preventing distortions that could affect image resolution and sample integrity.

 

AutoGrid Rings & C-Clips are widely used in structural biology, molecular imaging, and material sciences, providing a seamless workflow from sample preparation to high-resolution imaging.

Key Features of AutoGrid Rings & C-Clips

1. Precision-Engineered for Cryo-EM Applications

  1. Designed for Thermo Fisher Scientific Autogrids, ensuring seamless compatibility.
  2. Provides secure grid mounting, minimizing grid movement during imaging.
  3. Enables high-throughput Cryo-EM data collection with optimized workflow integration.

2. Durable Construction & Cryogenic Stability

  1. Constructed from high-quality, cryo-compatible materials to prevent distortion.
  2. Withstands extreme cryogenic temperatures without compromising integrity.
  3. Minimizes sample loss, ensuring consistent and reproducible imaging results.

3. Optimized for Automated Grid Handling & Preparation

  1. Reduces manual handling, decreasing the risk of grid damage and contamination.
  2. Compatible with fully automated Cryo-EM autoloader systems.
  3. Allows precise alignment for improved imaging efficiency.

4. Reliable C-Clip Locking Mechanism

  1. C-clip rings provide a firm hold, preventing grid dislocation or misalignment.
  2. Reduces thermal drift, ensuring better Cryo-EM image resolution.
  3. Enables faster and more efficient sample preparation for Cryo-EM workflows.

Technical Specifications of AutoGrid Rings & C-Clips – Essential Components

AutoGrid Rings & C-Clips Specifications
FeatureSpecification
MaterialHigh-Precision Cryo-Compatible Alloy
CompatibilityThermo Fisher Scientific Autogrids
Grid Locking MechanismSecure C-Clip Locking System
Temperature StabilityMaintains Integrity in Cryogenic Conditions
ApplicationsCryo-EM, TEM, High-Resolution Electron Microscopy
Automation CompatibilityFully Compatible with Cryo-EM Autoloaders

Applications of AutoGrid Rings & C-Clips

1. Cryo-EM Sample Preparation & Grid Handling

  1. Enables secure mounting of TEM grids for cryogenic electron microscopy.
  2. Minimizes sample drift, optimizing high-resolution imaging results.

2. Structural Biology & Drug Discovery Research

  1. Used for imaging protein structures, viruses, and macromolecular complexes.
  2. Essential in pharmaceutical and drug discovery applications.

3. High-Resolution Electron Microscopy (EM)

  • Compatible with transmission electron microscopes (TEM) for cryogenic imaging.
  • Optimizes imaging workflows in single-particle analysis and Cryo-ET studies.

4. Material Science & Nanotechnology Applications

  1. Supports precise imaging of nanomaterials, polymers, and thin films.
  2. Ensures sample stability in low-dose electron imaging techniques.

Why Choose AutoGrid Rings & C-Clips?

  1. Designed for Thermo Fisher Scientific Autogrids – Ensures perfect compatibility with leading Cryo-EM systems.
  2. Secure Grid Locking Mechanism – Prevents grid shifting, distortion, and sample loss.
  3. Cryogenically Stable & Durable – Built to withstand extreme low-temperature conditions.
  4. Optimized for Automated Workflows – Enhances high-throughput Cryo-EM imaging efficiency.
  5. High-Precision Manufacturing – Provides consistent, reproducible results for Cryo-EM research.
  6. Minimizes Beam-Induced Motion – Reduces thermal drift, improving image resolution.
  7. Trusted by Leading Cryo-EM Laboratories Worldwide – Proven performance in biological and material science imaging.

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